The AV 2025 APEX 50
Companies we are proud to own.
We are pleased to announce our AV 2025 Apex 50. This selection of 50 ventures from Alumni Ventures’ portfolio of over 1,500 current and historical investments represents some of the names we’re most excited about heading into 2025. These companies were selected for their innovative impact, outstanding performance, and potential upside.
As one of the most active venture capital firms globally, AV routinely co-invests alongside top lead investors, helping to ensure our portfolio reflects high-caliber opportunities. We’re proud to back stellar companies such as Groq, Rigetti, Lambda, Oura, and Bluesky. Please explore the Apex 50 list of amazing ventures in sectors ranging from next-generation nuclear power to quantum computers, AI-driven drug discovery, space logistics, brain-computer interfaces, fusion technology, AI hardware, cloud storage, blockchain analytics, defense tech, and more.
The AV 2025 APEX 50
HawkEye 360
Operates a satellite constellation that collects RF signals
- Awarded $12.25M by U.S. government
- Space Flight Laboratory recently confirmed deployment of satellites
Co-investor: Insight Partners
Oura
Captures and optimizes personalized biometric data
- Partners with brands such as NBA, Equinox
Co-investor: Gradient Ventures
Bluesky
Decentralized social media platform offering greater data control
- User base rose 763% in 2024
- Customizable algorithms, and an open ecosystem to foster transparency
Co-investor: Bain Capital
Pacific Fusion
Redefining fusion energy landscape
- Aims to deliver affordable, clean energy
Co-investor: General Catalyst
Lambda
AI infrastructure company
- Recognized four years in a row as NVIDIA Partner of the Year
Co-investor: Gradient Ventures
Enable
Provider of rebate solutions
- Manages, tracks, and analyzes rebates more efficiently, from agreement to payment
Co-investor: Menlo Ventures
Wasabi
Provides hot cloud storage
- Competes against Amazon’s S3 cloud storage while performing at 6x speeds and 1/5th the price
- Led by a seven-time founder
Co-investor: Fidelity Investments
Sleeper
Transforming fantasy sports
- Over 5 million monthly active users
- Launched “Sleeper Media”
Co-investor: Andreessen Horowitz
SHINE Technologies
Revolutionizing medical isotope production
- Generating critical materials for cancer treatment and medical imaging
- Roadmap transitions from medical isotopes to nuclear waste transmutation, then fusion power generation
- Already producing 100,000 doses annually of cancer-fighting lutetium-177
Co-investor: Oaktree Capital
Pendulum
Microbiome therapies for metabolic diseases
- Targeted formulations of natural bacterial strains help to rebalance the microbiome to restores and improve health
Co-investor: Sequoia Capital
Yassir
Rapidly expanding “super-app”
- Provides on-demand services such as ride-hailing, delivery, and financial solutions across North Africa and other emerging markets
- 8M+ app downloads and 2M monthly active users
Co-investor: Y Combinator
Honor
Software to improve in-home senior care
- Exceptional revenue growth
- Proven management team
Co-investor: Andreessen Horowitz
SonderMind
Mental health access through AI-driven tools
- Scaling rapidly while delivering innovative mental health solutions
- $77B+ market size
Co-investor: General Catalyst
Unstructured
AI-driven platform that turns unstructured data into actionable
insights
- Fast Company’s Most Innovative Company (2024) and Forbes AI 50
- Adoption by Fortune 500 companies; used by 50K companies
Co-investor: Bain Capital, Menlo Ventures
Kapital
Modernizing financial services for Latin American SMBs
- Combines access to capital with powerful business management tools
- Serving over 90,000 customers
Co-investor: Tribe Capital
Axiom Space
Private space flights and missions
- Building the first commercial successor to the ISS, democratizing space access for space agencies and nations, while enabling corporate R&D, manufacturing, and space tourism
- Billions in secured contracts
Co-investor: Prime Movers Lab
Enfabrica
Chip and cloud optimization
- Designs networking chips, systems, and software for AI computing
- Helps AI chips work more efficiently
Co-investor: Spark Capital, NVIDIA
Method
Provides tools that give fintechs and lenders seamless access to consumer credit and debt accounts
- Offers customers frictionless debt repayment options directly in apps
- Has helped 200,000+ users connect $22 billion
Co-investor: Andreessen Horowitz
Cents
Vertical SaaS platform for laundry operators
- Partnerships with Uber, DoorDash, and residential operators
- Minimal churn
Co-investor: Tiger Global
Forta Health
Family-powered autism support
- Transforming adolescent and family mental health care
- Contracted with seven of the top 10 largest U.S. health insurers
Co-investor: Insight Partners
Synchron
Developer of brain-computer interfaces
- Designed to restore motor function in individuals
- Significant strides in clinical trials
Co-investor: Khosla Ventures
Iambic
AI-driven biotech and drug design
- Address complex drug design challenges
- Platform has outperformed Google’s AlphaFold
Co-investor: Sequoia Capital
Atom Computing
Developer of large-scale quantum computers
- Using atomic arrays of optically-trapped neutral atoms
- Considered the first to reach the 1,000-qubit milestone
Co-investor: Google Ventures
Fleet
Mineral exploration via satellite
- Mineral exploration solution that combines satellite connectivity, 3D imaging, and AI
- Also generating substantial revenue from defense
Co-investor: Horizon Ventures
Centaur Health
Revolutionizing radiotherapy
- Secured millions in orders from leading cancer centers
- Received regulatory clearance
Co-investor: Deerfield Partners
TRM Labs
Market leader in blockchain analytics
- Helping detect and mitigate risks
- Adoption by PayPal, Visa, and FBI to name a few
Co-investor: Bessemer Venture Partners
Impulse Space
Pioneering in-space transportation market
- Solutions for satellite deployment and orbit transfers
- Significant government, commercial contracts, and
partnerships (DOD, Vast, Anduril)
Co-investor: Founders Fund
Surge
Groundbreaking drug delivery platform
- Partnerships across leading oncology centers
- Enables precise targeting of solid tumors, using localized drug release to minimize side effects and maximize efficacy
Co-investor: Khosla Ventures
Opus Clip
AI-powered video editing platform
- Supporting over 6 million creators and businesses
- Combines ease of use, superior products, and growing data moat
Co-investor: DCM Ventures, Millennium New Horizons, Samsung Nex
Nixtla
Forecasting & anomaly detection tools
- Flagship product trained on over 100 billion data points
- Reduces uncertainty and enables data-driven decision-making across industries, including financial, weather, energy, and web data
Co-investor: True Ventures, Microsoft
Altera
AI characters for gaming
- Partnered with major gaming studios and Open AI
- Unveiled an agent capable of playing Minecraft
Co-investor: Andreesen Horowitz
Sahara
Decentralized AI blockchain platform
- Enables freely and securely deploying autonomous AI with a high-performance, privacy-first network
- Addressing complex copyright and privacy concerns tied to AI
Co-investor: Pantera Capital
Railway
Intuitive platform that automates infrastructure management
- Scaled to 50,000+ developers; launched 900K+ projects
- Intuitive platform automates infrastructure management and eliminates the need for deep DevOps expertise
Co-investor: Redpoint Ventures
Frore Systems
World’s first solid-state active cooling chip for personal devices
- Awarded CES 2023 Best in Show
- Board includes 15x Midas List investor
Co-investor: Fidelity
Rwazi
AI-powered market intelligence in emerging markets
- Scaled revenue 6x in 24 months
- Customers include Red Bull, Nestle, and Estee Lauder
Co-investor: Bonfire Ventures
Ascend Elements
Proprietary recycling process for lithium-ion EV batteries
- Recovers / reuses cathode materials
- Plans to produce >99% pure, sustainable lithium carbonate from used lithium-ion batteries
Co-investor: BlackRock
Mysten Labs
Cutting-edge Layer 1 technology
- Offers high scalability, low latency, and cost efficiency
- Releasing Web 3 gaming device in 2025
Co-investor: Binance Labs
Rigetti
Superconducting quantum integrated circuits
- Also building software to integrate quantum computing into existing cloud infrastructure
Co-investor: Y Combinator
Download The AV 2025 Apex 50 to explore the full list of ventures and learn more about their groundbreaking work.
America’s Largest VC Firm for Individual Investors
No representation is intended that any investment or outcome shown is or would be representative of any AV fund or the outcomes experienced by any AV investor. The Apex 50 portfolio companies are provided for illustrative purposes only, and are not available to future investors except potentially in the case of follow-on investment. Venture capital investing involves substantial risk, including risk of loss of all capital invested. This communication is neither an offer to sell, nor a solicitation of an offer to purchase, any security. Such offers are made only pursuant to the formal offering documents for the fund, which describe the risks, terms, and other information that must be carefully considered before an investment is made.