Alumni Ventures Invests in Nanochon to Revolutionize Joint Repair with Advanced Implants

Nanochon CEO Benjamin Holmes Recently Discussed His Company on AV’s Tech Optimist Podcast

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Alumni Ventures (AV), one of the world’s most active venture capital firms, is a proud investor in Nanochon. The company is aiming to transform the treatment of cartilage damage and loss in joints (especially knees), with a groundbreaking implant that offers a promising new tool for those looking at knee replacement surgery. AV recently invested in Nanochon’s $4 million seed round led by The University of Virginia Licensing and Ventures Group Seed Fund, with participation from Cultivate (MD), Mountain State Capital, and others.

Knee replacement surgeries have become the most common elective surgery in the U.S., surpassing hip replacements. These procedures are often invasive, costly, and entail a lengthy recovery period, making them unsuitable for younger, more active individuals.

Nanochon has designed an implant to treat traumatic and arthritic cartilage damage in a minimally invasive manner. This implant offers immediate weight-bearing capabilities and promotes the regeneration of both cartilage and bone tissue, significantly reducing recovery times.

Tech Optimist Episode 16

A Discussion on the Future of Knee Replacements

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“Our goal is to provide a viable alternative to knee replacement surgery, especially for younger, active patients who require a solution that allows them to maintain their quality of life,” said Nanochon CEO Benjamin Holmes, who recently discussed his company on AV’s Tech Optimist podcast. “With the support of firms like Alumni Ventures, we are well-positioned to make significant strides in bringing our technology to market and improving patient outcomes.”

“Our goal is to provide a viable alternative to knee replacement surgery, especially for younger, active patients who require a solution that allows them to maintain their quality of life.”
Benjamin Holmes
CEO, Nanochon

Nanochon’s technology focuses on addressing focal cartilage lesions — localized areas of damage that resemble potholes in the joint. The implant, which mimics the collagen structure of natural cartilage, is engineered to integrate seamlessly with the body’s own cells, promoting the growth of new, healthy tissue. This breakthrough approach has shown promising results in preclinical studies, including tests on horses and goats, demonstrating the implant’s efficacy and durability.

Nanochon will use its recent seed funding for clinical trials, regulatory approvals, and further development of its innovative implant technology. The company is preparing for its first human clinical trial, set to begin in the fall, with a small safety study involving 10 patients. This pivotal milestone marks the transition from extensive preclinical research to real-world clinical application.

“We believe Nanochon’s technology has the potential to transform the lives of millions of patients,” said AV Founder and CEO Mike Collins, who hosted the conversation with Holmes on AV’s Tech Optimist podcast. “Ben and his team are addressing a significant unmet need in the medical field, and we are proud to be part of their journey.”

About Nanochon

Nanochon has created a novel orthopedic implant that encourages the growth of new cartilage, specially designed for patients who want to avoid surgeries like total knee replacements. Its proprietary, 3D-printed nanomaterial implant is minimally invasive and has potential to deliver faster and more successful recoveries while reducing costs to health providers, payers, and patients. Learn More »

About Alumni Ventures

Alumni Ventures offers accredited individuals access to professional-grade venture capital, a key asset class missing from the portfolios of many sophisticated investors. Since 2014, AV has raised $1.3+ billion from 10,000+ investors and backed 1,300+ unique portfolio companies. AV is a top 20 VC firm in North America according to CB Insights and the #1 most active VC firm in the U.S., and #3 most active in the world, according to PitchBook’s 2022 and 2023 rankings. AV has won awards from Inc. Magazine, Fast Company, Benzinga, and the US FinTech Awards. AV funds are private, for-profit, and not affiliated with or sanctioned by any school.

About Tech Optimist

The Tech Optimist Podcast, presented by Alumni Ventures (AV), focuses on the intersection of technology, entrepreneurship, and innovation. True to our name, we are passionate about technology and its potential to drive positive change. We explore our lane through interviews with founders, investors, and futurists; discussions of new innovations; and reviews of trends in tech and venture capital. Subscribe Here »

Media Contact Info
Scott Murphy
Alumni Ventures
670 N. Commercial Street, Suite 403
Manchester, NH 03101
Email: [email protected]

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Contact [email protected] for additional information. To see additional risk factors and investment considerations, visit av-funds.com/disclosures.